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Margin Following are a selection of Abstracts from Spine, V 24, No 9, May 1, 1999
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Phenotypic Characteristics of Rabbit Intervertebral Disc Cells: Comparison With Cartilage Cells From the Same Animals
Serge Poiraudeau, Irene Monteiro, Philippe Anract, Odile Blanchard, Michel Revel, and Marie Therese Corvol

The phenotypes of intervertebral disc cells were compared with articular and growth plate chondrocytes. Study data suggest that cells from the anulus fibrosus could be chondrocytic at a different stage of differentiation than cartilage cells, whereas the phenotype of the cells from the nucleus pulposus remains to be determined.

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Behavioral and Morphologic Studies of the Chronically Compressed Cauda Equina: Experimental Model of Lumbar Spinal Stenosis in the Rat
Kiyoshi Yamaguchi, Masazumi Murakami, Kazuhisa Takahashi, Hideshige Moriya, Hozumi Tatsuoka, and Tanemichi Chiba

An experimental model of rats with chronic compression of the cauda equina was produced, and behavioral and morphologic changes were examined. Walking durations decreased after chronic compression. However, paw withdrawal latencies were not significantly changed. Histologic evaluation indicated that the continuous degeneration and regeneration of axons occurred throughout the experiment.

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The Efficacy of Anterior Cervical Plating in the Management of Symptomatic Pseudoarthrosis of the Cervical Spine
Clifford B. Tribus, Darren P. Corteen, and Thomas A. Zdeblick

Anterior resection of cervical pseudoarthrosis with reconstruction using autogenous iliac crest bone grafting and anterocervical plating was performed in 16 consecutive patients. Fusion was graded I or II in 81% of patients, whereas stability was obtained in all patients. Clinical improvement of symptoms was demonstrated in 75% of patients.

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Active Back School: Prophylactic Management for Low Back Pain: A Randomized, Controlled, 1-Year Follow-Up Study
Jan H. Lønn, Bredo Glomsrød, Margreth G. Soukup, Kari Bø, and Stig Larsen

Active Back School as prophylactic management for low back pain proved effective in a randomized, controlled, 1-year follow-up study. New recurrences of low back pain and days of sick leave because of low back pain were reduced significantly, and general low back function and basic ergonomic functions significantly improved. Additionally, low back pain and quality of life showed a positive tendency.

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Return to Work After Surgery for Lumbar Disc Herniation: A Rehabilitation-Oriented Approach in Insurance Medicine
Peter Donceel, Marc Du Bois, and Dirk Lahaye

Sixty medical advisers of a sickness fund were assigned randomly into two groups and asked to guide a mandatorily insured patient population after open discectomy for herniated lumbar intervertebral disc until 1 year after surgical intervention. The intervention group (n = 30), which had to focus primarily on early mobilization, increased the probability for work resumption significantly in comparison with the control group (n = 30).

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Factors in the Reproducibility of Electromyographic Power Spectrum Analysis of Lumbar Paraspinal Muscle Fatigue
Antoni V. F. Nargol, Anthony P. C. Jones, Peter J. Kelly, and Charles G. Greenough

This study examines the reproducibility of lumbar paraspinal electromyographic testing in 39 individuals using several variables. The results show initial median frequency and half-width to have acceptable reproducibility over time and to be the least affected by a change in load. Posture was found to affect results greatly.

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Restorative Exercise for Clinical Low Back Pain: A Prospective Two-Center Study With 1-Year Follow-up
Scott Leggett, Vert Mooney, Leonard N. Matheson, Brian Nelson, Ted Dreisinger, Jill Van Zytveld, and L. Vie

Two similar chronic back pain patient populations were compared at centers in San Diego and Minneapolis. The same equipment and treatment protocol was used in both centers. Results of effectiveness as measured by strength testing and SF-36 were very similar at both centers, and the efficacy of benefit over a 1-year period was confirmed by minimal reuse of the health care services.

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Metal Debris From Titanium Spinal Implants
Jeffrey C. Wang, Warren D. Yu, Harvinder S. Sandhu, Foster Betts, Sunita Bhuta, and Rick B. Delamarter

Metal particulate "wear debris" was found in the paraspinal soft tissues, generated by the use of pedicle screw instrumentation. Higher concentrations were found in patients with a pseudarthrosis, whereas negligible levels were present in patients with a solid fusion. A mild macrophage response was discovered by electron microscopy and histologic studies.

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Scoliosis Secondary to Cerebrocosto-mandibular Syndrome: A Case Report With Surgical Management
Robert B. Winter and Beth Ann Bloom

A 9-year-old girl with cerebrocosto-mandibular syndrome, a very rare disorder with micrognathia and rib defects (short ribs with pseudarthroses near the costo-transverse junction), initially was seen by the author for a severe and progressive spinal deformity and progressive respiratory compromise. Surgery consisted of a T12 to S1 anterior and T3 to S1 posterior fusion with segmental instrumentation. Despite a preoperative vital capacity of 21% of the normal value, there were no complications, and the patient was doing well at 3 years after surgery.

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Occipital Pain in Osteoid Osteoma of the Atlas: A Report of Two Cases
Mania P. De Praeter, Guido F. Dua, Patrick C. Seynaeve, Dirk G. Vermeersch, and Robert L. Klaes

Osteoid osteoma of the atlas is very rare. Two cases of occipital pain caused by an osteoid osteoma of the atlas are presented.

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Nerve Root Herniation Secondary to Lumbar Puncture in the Patient With Lumbar Canal Stenosis: A Case Report
Kazuhiro Hasegawa and Noriaki Yamamoto

This report describes a very rare case of lumbar canal stenosis in a 66-year-old woman with a nerve root herniation secondary to lumbar puncture. The puncture should not be carried out in an area of stenosis.

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Anterior Disc Protrusion as a Cause for Abdominal Symptoms in Childhood Discitis: A Case Report
John K. Wong-Chung, Shaheed A. Naseeb, Sangam G. Kaneker, and Ali J. Aradi

Previous studies have correlated posterior herniation of disc phlegmon in childhood discitis with a clinical picture of back pain, stiffness, hamstrings tightness, and radiculopathy. None has connected anterior protrusion with abdominal pain. The authors describe a case of infectious spondylitis in a 6-year-old child with abdominal pain caused by anterior herniation of disc phlegmon.

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Advances in Spinal Cord Regeneration
Jike Lu and Phil Waite

Spinal cord injury continues to be a major cause of morbidity in our society. Recent experimental approaches to spinal cord trauma in animals are showing that some functional recovery is possible even after complete transections. This review outlines these new advances and discusses their implications for management of spinal cord disorders in humans.

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